Links:  Subscribe to PREMIUM to get study notes to this episode Go to episode page to see background detail & links See our recommended resources for further learning  Previous episodes referenced:  SNP17: Is Personalized Nutrition Superior to General Nutrition Advice? 414: Will Machine Learning Overtake Traditional Nutrition Research Methods? 469: Chrononutrition – New Findings & Updated Views  About This Episode: To mark the 500th episode of the podcast, Danny and Alan take a look at some of the current outstanding questions in nutrition science, what areas have largely been resolved, and how their own thinking has evolved and changed over time.  This brings them into areas such as personalized nutrition, ultra-processed foods, time-restricted eating, salt & health, and the difference between being “evidence-based” and “reference-based”. We Discuss:  Outstanding questions in nutrition science  Personalized nutrition Ultra-prosessed foods (UPFs) Diet-Microbiome-Health Omega-3 Fatty Acids   Largely resolved questions  Sodium & CVD risk TRE/TRF Macronutrient breakdown & weight loss   Evolution in our thinking  Epistemology at the forefront “Reference-based” to evidence-based Reading research: understanding “highest quality evidence”

#500 – The Big Unanswered Questions in Nutrition Science

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